You have so many options when it comes to choosing a ORM these days. My personal favorite is nHibernate I have been using nHibernate for a few years now and I find it flexible really easy to use and has a growing community of users. Saying that I'm always on the lookout for something new which is where OpenAcess ORM form Telerik comes in, I use the Telerik RadControls for ASP.NET AJAX on some projects.I have always found it a good practice to minimize the number different 3rd party control vendors in an application. You usually have less problems integrating the controls and have a more consistent product.